Mouse anti-CD71, clone MEM-75 - 0.1 mg

Description :CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clath rin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron. Applications :Flow Cyt | IP | ICC Species_reactivity :Human Clone :MEM-75 Clonality :Monoclonal Storage_Buffer :Tris buffered saline (TBS) solution with 15 mM sodium azide Concentration :1 mg/ml